BERC

Panagiotis Bargiotas

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SLEEP AND MOTION

LABORATORY

"Sleep and Brain Health"

Panagiotis Bargiotas, MD, is a physician-scientist and Assistant Professor in the Department of Neurology at the University of Cyprus Medical School, based in Nicosia, Cyprus. He received his clinical training and developed doctoral and postdoctoral work at the Universities of Heidelberg (DE) and Bern (CH). His research track includes basic research on mice models of stroke and clinical research on movement disorders, especially on deep brain stimulation. His current clinical and research broadly concentrates on the reciprocal interactions between sleep and motion - particularly on the neurobiology of sleep-wake disturbances in patients with neurodegenerative disorders (i.e. Parkinson’s disease) and stroke. He received research funding from several European and local funding agencies (EU Horizon, IRC Swiss, MSCA COFUND, ONISILOS EU), he enjoys editorial activities in several high-impact Journals and also mentoring/supervising activities at the University of Cyprus, at the University of Bern (CH) and the University of Athens (NUKA).

 

 

 

 

 

 

  

Assistant Professor Panayiotis Bargiotas

Medical School, University of Cyprus

Shacolas Educational Centre for Clinical Medicine

Nicosia, CY

This email address is being protected from spambots. You need JavaScript enabled to view it.; (+357) 22 895221

Neurobiology of

Sleep-wake Disturbances

My research primarily explores the neurobiology of sleep-wake disturbances in patients with Parkinson’s disease, neurodegenerative disorders, and stroke. My research approach integrates sleep neurophysiology, wearable technology for home-based and clinical assessments, and computational methodologies.methods including software to study both direct and indirect causal effects within the TRIP sociometric network.

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Impact of

Pharmacological non-Pharmacological and Interventional Treatments

Additionally, I continue my previous line of research investigating the impact of pharmacological, non-pharmacological, and interventional treatments, including deep brain stimulation, on gait and movement disorders. This research approach integrates Gait Analysis Systems, video-based oculomotor assessments and wearable technology.

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Sleep

Physical activity & Nutrition

During my recent tenure at the University of Cyprus, I have delvedimage4_bargiotis.png into the research areas of sleep, physical activity, and nutrition, complemented by newly established collaborations with the Departments of Life and Health Sciences and Sport Science (University of Nicosia, CY and University of Thessaly, Trikala, GR). This dynamic intersection of human well-being offers a promising avenue to apply cutting-edge wearable technology available in my lab, while also contributing to advancements in preventive healthcare, chronic disease management, and lifestyle optimization. I am excited to further pursue this research and strengthen these collaborations.

SELECTED GRANTS

  1. 2023, MSCA COFUND, ONISILOS EU Fellowship programme University of Cyprus, for postdoctoral positions

  2. 2018, Eurostars, Horizon 2020 Framework (Local Co-principal Investigator), Bern University, - 2017, Uni-Bern, Initiator Grant (principal investigator), Bern

  3. 2016, Young Researcher Research-Grant (Principal Investigator), University Hospital Bern

  4. 2017, IRC-Grant, NCCR (junior principal investigator), University of Bern

 
SELECTED PUBLICATIONS
  1. REM sleep and muscle atonia in brainstem stroke: a quantitative polysomnographic study. Tellenbach N., Schmidt M., Alexiev F., Blondiaux E., Cavalloni F., Bassetti CL., Heydrich L., Bargiotas P. (Journal of Sleep Research, 2023)
  2. Long-Term Outcome and Neuroimaging of Deep Brain Stimulation in Holmes Tremor: A Case Series. Bargiotas P, Nguyen TAK, Bracht T, Mürset M, Nowacki A, Debove I, Muellner J, Michelis JP, Pollo C, Schüpbach WMM, Lachenmayer ML. 2021 Jan 3. doi: 10.1111/ner.13352.
  3. Effects of bilateral stimulation of the subthalamic nucleus in Parkinson's disease with and without REM sleep behaviour disorder. Bargiotas P, Debove I, Bargiotas I, Lachenmayer ML, Ntafouli M, Vayatis N, Schüpbach MW, Krack P, Bassetti CL. J Neurol Neurosurg Psychiatry. 2019 Dec;90(12):1310-1316.
  4. Sleepiness and Sleepiness Perception in Patients with Parkinson’s Disease: A Clinical and Electrophysiological Study. P. Bargiotas, M. Lachenmayer, David R. Schreier, Johannes Mathis, Claudio L. Bassetti. Sleep. 2019 Apr 1;42(4).
  5. Pannexins in ischemia-induced neurodegeneration. Panagiotis Bargiotas, Antje Krenz, Sheriar G. Hormuzdi, Dirk A Ridder, Anne Herb, Waleed Barakat, Silvia Penuela, Jakob von Engelhardt, Hannah Monyer, Markus Schwaninger. Proc Natl Acad Sci (PNAS). 2011 Dec 20;108(51):20772-7.